Sendatu Therapeutics is driven by a singular mission: to bioengineer the next generation of adeno-associated virus (AAV) capsids to unlock the true potential of gene therapy.
Gene therapy represents a revolutionary approach to medicine, treating or curing genetic diseases by delivering corrective genetic material directly into a patient’s cells. However, the industry faces a massive delivery bottleneck. These therapies rely on microscopic delivery vehicles—known as AAV capsids—to transport the genetic payload. Unfortunately, naturally occurring AAV capsids often exhibit poor targeting efficiency, meaning they struggle to reach the specific tissues that need treatment. This lack of precision often requires administering high doses, which can trigger severe immune responses and toxicity in patients.
To solve this, Sendatu Therapeutics utilizes a proprietary bioengineering platform designed to build fundamentally better delivery vehicles. We actively address the poor efficiency and immunogenicity of current capsids by combining advanced artificial intelligence with cutting-edge vectorology techniques. Our AI-guided workflows computationally evaluate and engineer entirely new capsids, allowing us to accurately identify the safest, most efficient, and highly targeted candidates for any given therapeutic application.
Why work with us
Partnering with Sendatu Therapeutics grants you access to an advanced R&D engine specifically designed to bridge the clinical "translational gap"—the frequent and costly failure of therapies as they move from preclinical models into human trials.
We know that every therapeutic program is unique, which is why we do not offer a one-size-fits-all service. Instead, we meet you exactly where you are in your development journey. We work collaboratively with your team to identify the most relevant and predictive selection models for your specific application.
Furthermore, our platform is uniquely designed to select capsids based on the precise attributes most critical to the success of your specific therapy. Whether your application requires optimizing for the initial delivery of the genetic payload or maximizing the actual expression of that gene within the target cell, our platform isolates the candidates that perform exactly how you need them to.
When you partner with Sendatu, you are backed by a dedicated team of recognized experts spanning bioinformatics, machine learning, and vectorology. We provide the specialized expertise and the bespoke delivery technologies required to de-risk your pipeline, overcome clinical hurdles, and accelerate your path to delivering life-changing genetic medicines.
